Dendrimer Graft Hyperbranched Hydrogels
A novel dendrimer graft hyperbranched hydrogel was developed as a potential candidate for the biomedical applications. This hydrogel was composed of a first generation aliphatic polyester dendrimer and the DTPA (diethylenetriaminepentaacetic acid) moieties. This hydrogel showed a few very unique properties compared to the linear cross-link hydrogels. The hydrogel aggregated to give very uniform size in the acidic and neutral conditions. The average diameter of the particle size is about 15 μm, whereas in the basic conditions, the particle size of this hydrogel deaggregated to 400 nm without any treatment after four days. SEM results suggested that this is the result of a dimer product.