Fiber-optics based Optical Coherence Tomography for Biomedical Application
Optical coherence tomography (OCT) is a fast evolving noninvasive imaging technology for biomedicine in recent years. Its fundamental principle is to use a low coherent light on biological sample and collect the backscattering light with an interferemeter configuration. It can achieve high spatial resolution of several micrometers and reconstruct two or three-dimensional images with various scanning mechanisms. Based on a fiber-optics based OCT, we implemented an optical delay-line on the reference arm for fast scanning speed and a handheld probe on sampling arm for surface scanning applications. We also reported a simple image compensation scheme, which is based on the distortion profile of scan depth, to enhance the image quality.